Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medecine
Dr. Markus Axer, Head of the Fiber Architecture Group

Image acquisition in a polarimetric setup. The optical filters (two linear polarizers and one quarter-wave retarder) are synchronously rotated relative to the brain section placed in-between. The birefringent fiber structures induce characteristic sinusoidal changes in the transmitted light intensity (left). Section- and pixel-wise analysis of the measured sinusoidal signals result in a color-coded description of fiber orientations referred to as fiber orientation map (right).
© INM-1, Forschungszentrum Jülich


The hippocampus of birds in a view of evolutionary connectomics.

Teaching NeuroImages: In vivo visualization of Edinger comb and Wilson pencils.

Ex Vivo Visualization of the Trigeminal Pathways in the Human Brainstem Using 11.7T Diffusion MRI Combined With Microscopy Polarized Light Imaging

Direct Visualization and Mapping of the Spatial Course of Fiber Tracts at Microscopic Resolution in the Human Hippocampus.

SOUND : Prof. Dr. med. Dr. h.c. Karl Zilles : die TAORAD Methode (Jülicher Festvortrag 2009, Prof. Zilles 2020)

MOVIE : 3D-PLI rat brain
Schubert, Axer, Schober, Huynh, Huysegoms, Palomero-Gallagher, Bjaalie, Leergaard, Kirlangic, Amunts, Zilles (2016). 3D Reconstructed Cyto-, Muscarinic M2 Receptor, and Fiber Architecture of the Rat Brain Registered to the Waxholm Space Atlas. Frontiers in Neuroanatomy 10:51