polarized light microscopy

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Forschungszentrum Jülich GmbH, Institute of Neuroscience and Medecine
Dr. Markus Axer, Head of the Fiber Architecture Group

Image acquisition in a polarimetric setup. The optical filters (two linear polarizers and one quarter-wave retarder) are synchronously rotated relative to the brain section placed in-between. The birefringent fiber structures induce characteristic sinusoidal changes in the transmitted light intensity (left). Section- and pixel-wise analysis of the measured sinusoidal signals result in a color-coded description of fiber orientations referred to as fiber orientation map (right).
© INM-1, Forschungszentrum Jülich

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SOUND : Prof. Dr. med. Dr. h.c. Karl Zilles : die TAORAD Methode (Jülicher Festvortrag 2009, Prof. Zilles 2020)

3D PLI BRAIN ARCHITECTURES